CAR-T Cell Therapy Expansion into Autoimmune Diseases
For decades, treatment of severe autoimmune disease has largely followed a suppression-and-maintenance model. Corticosteroids, conventional immunosuppressants and biologic therapies can control inflammation and prevent organ damage, but many patients remain dependent on long-term treatment and may relapse when therapy is withdrawn. The possibility of eliminating the immune cells that sustain disease has therefore attracted intense…